Sequencing Larger Intact Proteins (30-70 kDa) with Activated Ion Electron Transfer Dissociation
نویسندگان
چکیده
منابع مشابه
Coupling capillary zone electrophoresis with electron transfer dissociation and activated ion electron transfer dissociation for top-down proteomics.
Top-down proteomics offers the potential for full protein characterization, but many challenges remain for this approach, including efficient protein separations and effective fragmentation of intact proteins. Capillary zone electrophoresis (CZE) has shown great potential for separation of intact proteins, especially for differentially modified proteoforms of the same gene product. To date, how...
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ژورنال
عنوان ژورنال: Journal of The American Society for Mass Spectrometry
سال: 2017
ISSN: 1044-0305,1879-1123
DOI: 10.1007/s13361-017-1808-7